绯栧翱鐥呭強鑲ヨ儢宸叉垚鐐哄叏鐞冩�х殑鍋ュ悍鍟�(w猫n)椤�锛岄毃钁椾汉鍊戝皪(du矛)閫欎竴鍟�(w猫n)椤岀殑閲嶈绋嬪害涓嶆柗鎻愬崌锛屾笡鑲ヨ棩鐗╁競鍫�(ch菐ng)鐔卞害涔熼枊(k膩i)濮嬫寔绾�(x霉)鏀�鍗�銆傛湁鏁�(sh霉)鎿�(j霉)椤ず锛屽埌2030骞�锛岄�欎竴甯傚牬(ch菐ng)鐨勮(gu墨)妯″皣閬�(d谩)鍒�1000鍎勭編鍏�銆傜洰鍓嶅彈鍏ㄧ悆娓涜偉钘ュ競鍫�(ch菐ng)瑕�(gu墨)妯℃寔绾�(x霉)澧為暦(zh菐ng)褰遍熆锛岀溇澶氬埗钘ュ法闋兘鍦ㄧ偤鍒嗗緱涓�鏉竟鑰屾埌(zh脿n)銆傚叾涓�锛屽�煎緱娉ㄦ剰鐨勬槸锛屾湁閮ㄥ垎浼佹キ(y猫)宸蹭笉鍐嶆妸鐩厜灞�闄愪簬鐪间笅鐏啽鐨勯澏榛�(di菐n)姗�(j墨)鍒讹紝姝ｅ湪鍔犻�熼��(j矛n)琛岃秴鍓嶅竷灞�銆�
銆�銆�濡�8鏈堜唤锛屽湪娓涢噸甯傚牬(ch菐ng)锛岃鍜岃寰峰氨宸叉帴閫ｅ嚭鎵�锛屽竷灞�椋熸鎶戝埗椤炶棩鐗�銆�8鏈�10鏃ワ紝璜惧拰璜惧痉瀹ｅ竷浠�10.75鍎勭編鍏冪殑鍍�(ji脿)鏍�锛屾敹璩�(g貌u)鍔犳嬁澶х敓鐗╂妧琛�(sh霉)鍏徃Inversago銆�
銆�銆�鎿�(j霉)浜嗚В锛孖nversago鐨勬牳蹇冪绶�锛屾槸涓�娆惧彛鏈岰B1鍙嶅悜婵�鍕�(d貌ng)鍔慖NV-202銆侷NV-202鑳藉鍎�(y艒u)鍏堥樆鏂峰鍛ㄧ祫绻�锛屽鑴傝偑绲勭箶銆佽儍鑵搁亾銆佽厧鑷熴�佽倽鑷�銆佽儼鑵恒�佽倢鑲夊拰鑲轰腑鐨勫彈楂旇泲鐧紺B1锛屾槸涓�娆炬經鍔涘崄瓒崇殑鈥滆惉(w脿n)閲戞补鈥濊棩鐗┿��
銆�銆�8鏈�30鏃�锛岃鍜岃寰峰甯冧互4.71鍎勬瓙鍏冪殑鍍�(ji脿)鏍兼敹璩�(g貌u)涓归亥鍏徃Embark Biotech锛屼互灏嬫眰鍦ㄨ摤鍕冪櫦(f膩)灞曠殑娓涜偉闋�(l菒ng)鍩熶繚鎸佸劒(y艒u)鍕�(sh矛)銆傞�氶亷(gu貌)姝ゆ鏀惰臣(g貌u)锛岃鍜岃寰风嵅寰楅枊(k膩i)鐧�(f膩)鍜屽晢妤�(y猫)鍖朎mbark Biotech鐨勫厛灏�(d菐o)浠ｈ瑵闋�(xi脿ng)鐩殑鍏ㄩ儴娆�(qu谩n)鍒╋紝骞跺悓Embark閫�(j矛n)琛岀偤鏈熶笁骞寸殑鐮旂櫦(f膩)鍚堜綔銆�
銆�銆�鍦ㄤ箣鍓嶇殑鎶湶涓紝Embark Biotech姝ｅ湪鐮旂┒涓�绋偉鑳栫櫏鐨勫皬鍒嗗瓙鈥滆兘閲忔秷鑰楁縺娲诲姂鈥�锛屼笉鍍呭叿鏈夎垏GLP-1鐩镐技鐨勬姂鍒堕娆茬殑鏁堟灉锛屽苟涓斿彲浠ュ鍔犺儼宄剁礌鐨勬晱鎰熸��锛屽姞寮�(qi谩ng)鑳介噺鐨勬秷鑰�銆�
銆�銆�闄や簡璜惧拰璜惧痉锛岀Ξ渚�(l谩i)鍦ㄦ笡鑲ヨ棩甯傚牬(ch菐ng)涔熷湪鍔犻�熷竷灞�銆�7鏈�14鏃�锛岀Ξ渚�(l谩i)瀹ｅ竷浠�19.25鍎勭編鍏冪殑鍍�(ji脿)鏍硷紝鏀惰臣(g貌u)浜嗛潪涓婂競鍏徃Versanis銆傛鑸夛紝姝ｆ槸鐐烘笡鑲ヨ棩鐨勫竷灞�娣荤鍔犵摝銆傛摎(j霉)鎮夛紝Versanis鐨勬牳蹇冪绶�锛屾槸涓�娆炬嫯鎶楁縺娲荤礌2鍨嬪彈楂擜/B鐨�(ACVR2A/B)鍠姉Bimagrumab锛岄�欐槸涓�绋湁鍒ヤ簬GLP-1鐨勬經鍔涙笡鑲ヨ棩銆�
銆�銆�Versanis姝ゅ墠鍏竷鐨勪簩鏈熻嚚搴婄祼(ji茅)鏋滄暩(sh霉)鎿�(j霉)椤ず锛屽湪绲﹁棩48鍛ㄥ悗锛孊imagrumab娌荤檪绲勭殑楂旈噸闆栧彧涓嬮檷浜�6.5%锛屼絾楂旇剛涓嬮檷骞呭害楂橀仈(d谩)20.5%銆傚苟涓�锛孊imagrumab鑸嘒LP-1涓�妯ｏ紝鎿佹湁涓嶆柗鎿�(ku貌)灞曢仼鎳�(y墨ng)鐧ョ殑鑳藉姏銆傛牴鎿�(j霉)Versanis鐨勮ō(sh猫)鎯�锛孊imagrumab鐨勯仼鎳�(y墨ng)鐧ラ枊(k膩i)鐧�(f膩)锛岄鍏堟槸鑲ヨ儢锛岀劧鍚庢槸鏇村唬娉涘湴鐢ㄤ簬蹇冭嚐浠ｈ瑵鐤剧梾銆�
銆�銆�鍊煎緱涓�鎻愮殑鏄�锛岀Ξ渚�(l谩i)鍦ㄤ笂鍗婂勾锛岄倓鍏竷浜嗗叾鍙ｆ湇鍊欓伕钘ョ墿orforglipron鐨勪簩鏈熻│椹�(y脿n)鏁�(sh霉)鎿�(j霉)锛岄’绀哄叾楂旈噸娓涜紩浜�14.7%锛屾瘮瑭插叕鍙哥洰鍓嶇殑2鍨嬬硸灏跨梾娉ㄥ皠鍔慚ounjaro椤ず鍑烘洿濂界殑鏁�(sh霉)鎿�(j霉)銆傜Ξ渚�(l谩i)鐨勭硸灏跨梾钘ョ墿Mounjaro鍦ㄥ幓骞翠簬缇庡湅(gu贸)琚壒婧�(zh菙n)鐢ㄤ簬骞姪2鍨嬬硸灏跨梾鎮ｈ�呮帶鍒惰绯栨按骞炽�傜洰鍓�锛岀Ξ渚�(l谩i)姝ｅ湪灏嬫眰FDA鎵规簴(zh菙n)灏嘙ounjaro浣滅偤涓�绋偉鑳栨不鐧傝棩鐗┿�傛摎(j霉)鎮�锛屽湪瑭﹂(y脿n)涓�锛岄珮鍔戦噺鐨凪ounjaro骞姪鎮ｈ�呮笡鎺変簡50纾呴珨閲�銆傛澶�锛岀Ξ渚�(l谩i)閭勫湪鐮旂┒鍏朵粬钘ョ墿绲勫悎锛屼互灏嬫眰鏇村ソ鐨勬笡鑲ユ晥鏋溿��
闂�(gu膩n)閸靛瓧锛氬埗钘ユ(j墨)姊板睍銆佸寘瑁濇(j墨)姊板睍銆佸埗钘ヨō(sh猫)鍌欏睍銆丆HINAPHARM銆佸(sh铆)椹�(y脿n)瀹よō(sh猫)鍌欏睍銆乧hina-pharm銆佸埗钘ュ伐绋嬪睍銆佸(sh铆)椹�(y脿n)瀹ゅ剙鍣ㄥ睍銆佽棩姗�(j墨)灞曟渻(hu矛)銆佸師鏂欒棩瑷�(sh猫)鍌欏睍銆佸埗钘ュ寘瑁濊ō(sh猫)鍌欏睍銆佽棩姗�(j墨)鏈�(hu矛)銆佽棩鐢ㄧ矇纰庤ō(sh猫)鍌欏睍銆佸埗钘ュ寘瑁濇(j墨)姊板睍銆佸埗鍔戣ō(sh猫)鍌欏睍銆佽棩姗�(j墨)灞曘�佽棩鐢ㄨō(sh猫)鍌欏睍銆佸埗钘ョ敤姘磋ō(sh猫)鍌欏睍銆佸(sh铆)椹�(y脿n)瀹よō(sh猫)鍌欏睍銆佸埗钘ユ(j墨)姊板崥瑕芥渻(hu矛)銆佸叏鍦�(gu贸)鍒惰棩姗�(j墨)姊板崥瑕芥渻(hu矛)銆佸噲鍖栬ō(sh猫)鍌欏睍銆佽棩鐢ㄦ娓�(c猫)瑷�(sh猫)鍌欏睍鏈�(hu矛)銆佸埗鍔戞(j墨)姊板睍銆佷腑钘ヨō(sh猫)鍌欏睍銆佸(sh铆)椹�(y脿n)瀹よō(sh猫)鍌欏睍銆佹綌鍑堣ō(sh猫)鍌欏睍銆佺敓鐗╁埗钘ヨō(sh猫)鍌欏睍銆乤pi鍘熸枡钘ュ睍銆侀啱(y墨)钘ヤ腑闁撻珨灞曘�佸埗钘ュ寘瑁濆睍銆佸埗钘ユ(j墨)姊板睍銆乤pi鍘熸枡钘ユ渻(hu矛)銆佽棩鐢ㄨ紨鏂欐渻(hu矛)銆侀啱(y墨)钘ュ寘瑁濆睍銆佸埗钘ヨō(sh猫)鍌欏睍銆佸師鏂欒棩鏈�(hu矛)銆佽紨鏂欓厤鏂欏睍銆佽棩鐢ㄧ幓鐠冨睍銆佸埗钘ュ伐绋嬪睍銆佸埗钘ュ師鏂欏睍銆佽棩鐢ㄨ紨鏂欏睍銆佸寘瑁濆嵃鍒峰睍銆佸寘瑁濊ō(sh猫)鍌欏睍銆侀啱(y墨)钘ュ師鏂欏睍銆佸彛鏈嶅浐楂斿埗鍔戝睍銆侀啱(y墨)钘ュ寘鏉愬睍銆佸(sh铆)椹�(y脿n)瀹ゅ剙鍣ㄥ睍銆佷腑鍦�(gu贸)鍦�(gu贸)闅涢啱(y墨)钘ュ師鏂欒棩/涓枔楂�/鍖呰/瑷�(sh猫)鍌欎氦鏄撴渻(hu矛)銆佺簿绱�(x矛)鍖栧伐灞�銆佹敞灏勫姂鍖呰灞曘�佸師鏂欒棩瑷�(sh猫)鍌欏睍銆丄PI China銆侀啱(y墨)钘ヤ腑闁撻珨灞�銆佷腑鍦�(gu贸)鍦�(gu贸)闅涢啱(y墨)钘ュ寘瑁濆睍銆佷腑鍦�(gu贸)鍦�(gu贸)闅涘埗钘ヨō(sh猫)鍌欏睍銆佷腑鍦�(gu贸)鍦�(gu贸)闅涜棩鐢ㄨ紨鏂欏睍銆丳HARMPACK銆佽棩姗�(j墨)鏈�(hu矛)PHARMEX銆丼INOPHEX